New discovery could lead to a treatment against human papillomavirus (HPV)

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‘This result confirms and validates the range HPV our range of compounds have shown antiviral activity in both DNA and RNA viruses. It ‘s rare to find a group of compounds target a wide range of viruses from different viral families. They are very exciting times for our shareholders, primary care physicians and patients with these diseases, for so long, waited for the drugs that are safe and effective, ‘Tamir said CEO Charles Muniz.Prescription drugs: Two drugs dominate the market for Genital Warts: Aldara, originally marketed by 3M and Graceway Pharmaceuticals sold in 2006, and Podofilox marketed by Watson Pharmaceuticals. Neither drug is the virus itself. They treat the symptoms of the virus.

Although there is currently no cure for the infection with human papillomavirus medical, benign lesions and warts these viruses cause can be treated. Another treatment is electrosurgical loop excision procedure , where the tissue is removed using a hot cycle flush. Even after treatment, genital warts can return. In fact, 25 % of cases within three months back.

Homosexual men are seventeen times more likely to develop anal cancer than heterosexual men.

View drug information Aldara; Cervarix [bivalent human papillomavirus, Gardasil.

‘The acceptance of our CTA by regulatory authorities in the Philippines and Malaysia provides Celsion with trial agreements in key countries where primary liver cancer is the most common. We have not reached an important milestone and are against the ‘ execution of our strategy to complete our Phase III study in HCC to provide a basis for the NDA submission in regions where liver cancer is endemic, ‘said Michael H. Tardugno, Celsion’s President and CEO. ‘We managed to get regulatory approval in 10 of the 11 targeted countries covering about 80 percent of HCC worldwide. With the increasing incidence of hepatocellular carcinoma with a ratio of 5 percent per year, the World Health Organization projects that it is No. 1 worldwide in 2020

Women, especially young people, have experienced the highest levels of HPV infections. An average of four % of American students are infected with genital HPV each year.

It ‘important to realize that Onconase, our lead compound, has been in clinical trials for other oncology indications, and has proven to be well tolerated in over 1000 patients treated to date. We can not stress enough how significant our safety profile of drugs is entering clinical trials that we look for the virus where we have reported significant antiviral activity without the toxicity levels inherent with other viral therapies.

Although vaccines have proven to be effective, they work before an individual is exposed to the virus. After exposure, vaccines have no therapeutic effect.

Periungual and subungual warts appear under and around toenails.

Over-the-counter drugs, three drugs used to treat common warts dominate the market: Dermisil, Condysil gel Wartrol. It is estimated that the whole wart medication on the market over-the-counter market is a multi-million dollars. These drugs are not recommended for genital warts.

According to the researcher to test, the results were among the top 1-2 % seen by the researcher to determine the HPV type 11. The report states: ‘. Excellent antiviral activity and no cellular toxicity at doses tested’

Flat warts are generally found on the face and forehead. They are common in children, less common in adolescents and rare in adults.

In the United States, cervical cancer in Hispanic women occurs at a rate that is twice that for non-Hispanic women.

Cervical cancer was once the leading cause of cancer death among women in the United States. However, the Pap test has helped to significantly reduce mortality in general. However, it is still the fifth leading cause of cancer deaths in women.

NIAID is a component of the National Institutes of Health Office of Medical Research of our nation. The NIH is the primary federal agency for conducting and supporting basic clinical research and translational medicine, and it investigates the causes, treatments and cures for both common and rare diseases. NIAID supports basic and applied research to prevent, diagnose and treat infectious diseases such as HIV / AIDS and other sexually transmitted diseases,,,, and disease from potential agents of bioterrorism.

Human Papillomavirus is the name of a group of viruses that includes more than 100 types. More than forty types of HPV can be transmitted through sexual contact.S. and worldwide.

In recent months we have reported significant results for our compounds against dengue, yellow fever, CMV, and now against HPV. We’re going to build an impressive portfolio that antivirals targeting viruses where there is currently an unmet need. Besides the fact that our drugs have shown significant antiviral activity against the viruses mentioned above, equally impressive is the fact that very low concentrations of our drugs are needed to demonstrate the antiviral activity significantly.

Vaccines: There are two vaccines to prevent infection by some types of HPV: Gardasil, marketed by Merck and Cervarix, marketed by GlaxoSmithKline. Both vaccines protect against initial infection, for HPV types 16 and 18 HPV cause cervical cancer. Vaccines work best when given to girls before their first sexual contact. Both vaccines are recommended for eleven and twelve o’clock, the girls. The vaccines are administered in a series of three shots. Between 2006 and the first half of 2009, sales of Gardasil were approximately $ 2.5 billion.

Tamir Biotechnology, Inc. announced that scientists supported by the National Institute of Allergy and Infectious Diseases reported test results confirming two of our lead compounds showed excellent activities In vitro antiviral and cellular toxicity at doses tested for human papillomavirus . The tests were performed using 11 strains of HPV, which, with HPV type 6, is responsible for ninety % of genital or anal.

HPV affects males and females. Transmission of HPV can occur with any type of genital contact with someone who has HPV. The report is not required for HPV. According to the Centers for Disease Control , approximately twenty million Americans are currently infected with HPV and another six million people are infected each year. HPV has become so common that at least fifty % of sexually active men and women will be infected with HPV at some point in their lives. Half of people with HPV are between fifteen and twenty-four

HPV is spread through sexual contact or, rarely, skin to skin contact during sexual acts. Genital warts, the most obvious sign of HPV infection, are highly contagious. About two thirds of people who have sex with a partner with genital warts will develop warts, usually within three months of contact.

Safe Harbor This press release contains statements that may constitute ‘forward-looking statements ‘, usually containing the words’ believe, ” estimate, ” project ‘,’ anticipate ‘or similar expressions. Forward-looking statements involve risks and uncertainties that could cause actual results to differ materially from such statements. The factors that cause or contribute to such differences include, but are not limited to, uncertainty whether the results of clinical studies will allow the company to complete the submission of a New Drug Application and if a submitting new drug application is complete uncertainty about the file or the FDA to approve this request, the uncertainties involved in the transition from concept to product, uncertainties regarding the company’s ability to fund research and development challenges and potential violations of patents, uncertainties about the ‘ outcome of clinical trials or differences of opinion in interpreting the results of clinical trials, the company’s ability to obtain necessary approvals of regulatory agencies, dependence on third party suppliers, and other risks discussed in filings made periodically by the company with the Securities and Exchange Commission.

The American Cancer Society estimates that in 2010 approximately 12 200 women in the U.S. will be diagnosed with invasive cervical cancer and about 4210 women in the U.S.

When it comes to HPV, there are four types of viruses we need to know. This is because these four types of cause most cases of HPV-related diseases in men and women. The types of HPV 16 and 18 cause about 75 percent of cervical cancer, 70 percent and 50 percent in females. HPV is thought to be the only cause of cervical cancer, and vaginal infections, and chronic urinary tract infections.

HPV has been linked to certain cancers and throat, cancer of the penis and cancer of the cervix.

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